Recombinant Human MAP1D Protein (His Tag)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSH032749-10, PKSH032749-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: MAP1D

Target Synonym: Methionine Aminopeptidase 1D Mitochondrial; Methionyl Aminopeptidase Type 1D Mitochondrial; METAP1D; MAP1D; MAP 1D; MetAP 1D; Metap1l

UNIProt ID: Q6UB28

Research Areas: Signal Transduction; epigenetics and nuclear signal;

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His & C-His

Accession: Q6UB28

Background: Methionine Aminopeptidase 1D (METAP1D) is a mitochondrion protein that belongs to the peptidase M24A family. METAP1D is overexpressed at the protein level in colon cancer cell lines and colon tumors as compared to normal tissues. N-terminal methionine removal is an important cellular process required for proper biological activity, subcellular localization, and eventual degradation of many proteins. METAP1D is also active with zinc, manganese or divalent ions. It may also play an important role in colon tumorigenesis.

Sequence: Arg44-Ala335

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 35.4 kDa

Observed MW: 35-40 kDa

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Research Use Only