RSMB rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES13325-50, ES13325-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq, Jul 2008],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human RSMB AA range: 42-92

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 6628

Human SWISS Prot NO: P14678

Subcellular Location: Cytoplasm, cytosol. Nucleus. SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.

Research Use Only