P63-α (3F11) Mouse mAb

Sizes: 50μL, 100μL

Catalogue Numbers: EM1404-50, EM1404-100

Citations, Manuals and MSDS Available upon request.

Background: p63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors . Research investigators frequently observe amplification of the p63 gene in squamous cell carcinomas of the lung, head and neck . The p63 gene contains an alternative transcription initiation site that yields a 40 kDa δNp63 lacking the transactivation domain, and alternative splicing at the carboxy-terminus yields the α, β, and γ isoforms .

Source: Mouse

Applications: WB, IHC

Dilution: WB 1:1, 000-2, 000   IHC:1; 100-1:200

Reactivity: Human, Rat, Mouse

Immunogen: Synthetic Peptide

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Monoclonal

Isotype: IgG1

Concentration: 1mg/mL

Observed Band (KD): 50-80kDa

Human Gene ID: 8626

Human SWISS Prot NO: Q9H3D4

Subcellular Location: Nucleus

Research Use Only