Gadobutrol (Gadovist, Gadavist) is a non-ionic macrocyclic gadolinium-based contrast agent (GBCA) that is usedfor tissue contrast enhancement in magnetic resonance imaging (MRI).

Product information

CAS Number: 770691-21-9

Molecular Weight: 604.71

Formula: C18H31GdN4O9

Synonym:

Gd-DO3A-butrol

ZK 135079

Gadograf

Gadovist

Gadavist

Protovist

Related CAS Number:

138071-82-6 (deleted cas)

Chemical Name: gadolinium(III) 2,2',2''-(10-((2R,3S)-1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate

Smiles: [Gd+3].[O-]C(=O)CN1CCN(CC([O-])=O)CCN(CCN(CC([O-])=O)CC1)[C@@H](CO)[C@@H](O)CO |&1:25,28|

InChiKey: ZPDFIIGFYAHNSK-YYLIZZNMSA-K

InChi: InChI=1S/C18H34N4O9.Gd/c23-12-14(15(25)13-24)22-7-5-20(10-17(28)29)3-1-19(9-16(26)27)2-4-21(6-8-22)11-18(30)31;/h14-15,23-25H,1-13H2,(H,26,27)(H,28,29)(H,30,31);/q;+3/p-3/t14-,15-;/m0./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Water: 100 mg/mL(165.36 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Lesley J Scott. Clin Drug Investig. 2018 Aug;38(8):773-784.

Products are for research use only. Not for human use.