USP2 Monoclonal Antibody

Catalogue Numbers: MB66738-50, MB66738-100

Sizes: 50µl, 100µl

Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: O75604

Host: Mouse

Reactivity: Human, Monkey

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove Ub, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP2 (Ub specific peptidase 2), also known as 41 kDa Ub-specific protease, is a 605 amino acid deubiquitinating enzyme that participates in the Ub pathway. Localized to the cytoplasm, USP2 forms a homooligomer and catalyzes the reaction of the Ub C-terminal thioester with water to form Ub and a thiol. USP2 is expressed as two isoforms produced by alternative splicing.

Purification and Purity: This antibody is purified through a protein G column.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of USP2 protein.

Extra Notes: Western blot analysis of USP2 expression in MCF7 (A), PC3 (B), COS7 (C), Du145 (D), SKBR3 (E) whole cell lysates.

Bioworld Molecular Weight: ~ 55 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: UBP41; Ubiquitin carboxyl-terminal hydrolase 2; 41 kDa ubiquitin-specific protease; Deubiquitinating enzyme 2; Ubiquitin thioesterase 2; Ubiquitin-specific-processing protease 2

Immunogen: Recombinant fusion protein of human USP2. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified