Ms-PEG7-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 109789-41-5

Molecular Weight: 482.56

Formula: C16H34O12S2

Chemical Name: 3, 6, 9, 12, 15, 18-hexaoxaicosane-1, 20-diyl dimethanesulfonate

Smiles: CS(=O)(=O)OCCOCCOCCOCCOCCOCCOCCOS(C)(=O)=O

InChiKey: HGSUQRYIYRXWTQ-UHFFFAOYSA-N

InChi: InChI=1S/C16H34O12S2/c1-29(17,18)27-15-13-25-11-9-23-7-5-21-3-4-22-6-8-24-10-12-26-14-16-28-30(2,19)20/h3-16H2,1-2H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.