Recombinant Human CFHR5 Protein (His Tag)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSH032274-10, PKSH032274-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: CFHR5

Target Synonym: Complement factor H-related protein 5; CFHR5; CFHL5; FHR5

UNIProt ID: Q9BXR6

Research Areas: immunology

Target Species: Human

Expression Host: HEK293 Cells

Fusion Tag: C-6His

Accession: Q9BXR6

Background: Complement factor H-related protein 5(FHR-5 for short), is a secreted protein which contains 9 Sushi (CCP/SCR) domains. It is expressed by the liver and secreted in plasma. The pattern of the deposits is similar to other complement components, suggesting that FHR-5 may play a role in complement activation and regulation. Defects in CFHR5 have been found in patients with atypical hemolytic uremic syndrome and may contribute to the disease. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease.

Sequence: Glu19-Glu569

Purity: > 90 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 63.5 kDa

Observed MW: 61 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only